Portfolio
Today a project: tomorrow a treatment
Partnering with IRICoR means leveraging OUR expertise, resources and network to accelerate YOUR drug discovery projects, reduce risks and improve the chances of a successful market launch.
Partnered
| indication | discovery | hit id | h2l | lead opt | ind enabling | clinical phase | partner |
|---|---|---|---|---|---|---|---|
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ex vivo cell expansion Cell transplant, Small molecule (UM-171) |
Phase 2 |
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PAR4 Thrombosis, Small molecule (UDM-003183, now BMS-986141) |
Phase 2 |
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PAR4 Thrombosis, Small molecule (UDM-002985, now BMS-986120) |
Phase 1 |
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Undisclosed #1 Solid Tumors, Small molecule |
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Tumor Specific Antigens Liquid and Solid Tumors, Therapeutic Cancer Vaccines |
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Undisclosed GPCR CV/HF, Small molecule |
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Melanocortin-4 receptor (MC4R) pharmacochaperone Metabolic disorder, Small molecule |
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Undisclosed #2 Solid tumors, Small molecule |
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Undisclosed GPCR IPF, Small molecule |
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ETC1 Leukemia and solid tumors, Small molecule |
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CoREST1 degrader Oncology, Small molecule |
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CyclinK degrader Oncology, Small molecule |
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Undisclosed degrader Aging (epigenetics), Small molecule |
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Partnering opportunities
| Indication | Discovery | Hit ID | H2L | Lead Opt | IND Enabling | Clinical phase | Academic Partner |
|---|---|---|---|---|---|---|---|
|
YES/SRC Dual kinase inhibitor Solid tumors, Small molecule |
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elF4A inhibitor Breast cancer and Solid tumors, Small molecule |
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Proteasome inhibitors Pediatric AML, Small molecule |
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SLAM7 Multiple Myeloma, mAb |
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mKEAP1/NRF2 inhibitor Chemoresistance, Small molecule |
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Neuraminidase Idiopathic Thrombocytopenic Purpura (ITP), Small molecule |
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ATG5 Metabolic Fitness Cell therapy, CAR-T |
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Undisclosed TSA AML, Monoclonal antibody |
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ERK3/4 Solid tumors, Small molecule |
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Undisclosed Solid tumors, Antibody drug conjugate |
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Undisclosed MAPK related target #1 Solid tumors, Small molecule |
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Undisclosed MAPK related target #2 Solid tumors, Small molecule |
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Drug Discovery Platforms / Tools
| Projects | Discovery | Validation -POC | In operation – Active-Functional – InForce | Commercialization | Partner |
|---|---|---|---|---|---|
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BRET Biosensors Drug Discovery Platform, BRET Biosensor |
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DNA Encoded Library (DEL) Drug Discovery Platform, DNA Encoded Library (DEL) |
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Multiplexed Biosensors Drug Discovery Platform, Biosensor Multiplexing Technology |
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